The invention provides methods of using CARD-4 molecules to screen for modulators of LPS-induced cell signaling pathways. Also included are CARD-4 deficient mice, methods of modulating LPS-induced cell signaling pathways, and methods of treating or preventing bacterial infections.
申请公布号
WO03097684(A8)
申请公布日期
2004.04.29
申请号
WO2003IB02597
申请日期
2003.05.22
申请人
INSTITUT PASTEUR;BERTIN, JOHN;PHILPOTT, DANA;SANSONETTI, PHILIPPE;GIRARDIN, STEPHEN
发明人
BERTIN, JOHN;PHILPOTT, DANA;SANSONETTI, PHILIPPE;GIRARDIN, STEPHEN
