发明名称 |
Aripiprazole complex formulation and method |
摘要 |
An aripiprazole formulation is provided which includes the antipsychotic agent aripiprazole in the form of an inclusion complex in a beta-cyclodextrin, preferably, sulfobutyl ether beta-cyclodextrin (SBECD), which in the form of an injectable produces reversible generally minimal to mild irritation at the intramuscular injection site. A method for minimizing or reducing irritation caused by aripiprazole at an intramuscular injection site and a method for treating schizophrenia employing the above formulation are also provided.
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申请公布号 |
US2004077594(A1) |
申请公布日期 |
2004.04.22 |
申请号 |
US20030642366 |
申请日期 |
2003.08.14 |
申请人 |
NERURKAR MANOJ;NARINGREKAR VIJAY;DOMINICK MARK |
发明人 |
NERURKAR MANOJ;NARINGREKAR VIJAY;DOMINICK MARK |
分类号 |
A61K31/19;A61K9/00;A61K31/496;A61K31/715;A61K31/724;A61K47/12;A61K47/48;C08B37/16;(IPC1-7):A61K31/724 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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