发明名称 METHOD FOR PRODUCING OPTICALLY ACTIVE 4-OXY-2-ARYL-2-ALKYLSILOXYBUTYRONITRILE
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a method for catalytically synthesizing an optically active 4-oxy-2-aryl-2-alkylsiloxybutyronitrile without using any highly toxic osmium compound. <P>SOLUTION: The method for producing the optically active 4-oxy-2-aryl-2-alkylsiloxybutyronitrile comprises carrying out a reaction of a compound of formula(I)( wherein, Ar is an aryl or heteroaryl; and R<SP>1</SP>is H or a hydroxyl-protective group ) with a cyanating agent in the presence of an optically active catalyst. <P>COPYRIGHT: (C)2004,JPO</p>
申请公布号 JP2004123624(A) 申请公布日期 2004.04.22
申请号 JP20020290889 申请日期 2002.10.03
申请人 SANKYO CO LTD 发明人 TAKAMURA MINORU;YABU KAZUO;YANAGISAWA HIROAKI
分类号 C07B53/00;C07B61/00;C07F7/18;(IPC1-7):C07F7/18 主分类号 C07B53/00
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