发明名称 |
METHOD FOR PRODUCING OPTICALLY ACTIVE 4-OXY-2-ARYL-2-ALKYLSILOXYBUTYRONITRILE |
摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method for catalytically synthesizing an optically active 4-oxy-2-aryl-2-alkylsiloxybutyronitrile without using any highly toxic osmium compound. <P>SOLUTION: The method for producing the optically active 4-oxy-2-aryl-2-alkylsiloxybutyronitrile comprises carrying out a reaction of a compound of formula(I)( wherein, Ar is an aryl or heteroaryl; and R<SP>1</SP>is H or a hydroxyl-protective group ) with a cyanating agent in the presence of an optically active catalyst. <P>COPYRIGHT: (C)2004,JPO</p> |
申请公布号 |
JP2004123624(A) |
申请公布日期 |
2004.04.22 |
申请号 |
JP20020290889 |
申请日期 |
2002.10.03 |
申请人 |
SANKYO CO LTD |
发明人 |
TAKAMURA MINORU;YABU KAZUO;YANAGISAWA HIROAKI |
分类号 |
C07B53/00;C07B61/00;C07F7/18;(IPC1-7):C07F7/18 |
主分类号 |
C07B53/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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