发明名称 Bio-reactor and cell culture surface with microgeometric surfaces
摘要 A bioreactor or cell culture surface comprises a multiplicity of microwells appearing, upon enlargement in the range of 200 to 1000 magnifications, as a honeycomb structure consisting of a plurality of rows of irregular hexagons, each having a transverse x-axis, a longitudinal y-axis, and a z-axis which defines a height of each microwell. Co-parallel major bases define the directionality of anticipated cell growth, while pairs of equilateral minor bases define the x-axis width of each microwell. An arrow-like geometry is defined by the equilateral pairs of minor bases which also define an x-axis separation between opposing major bases of the hexagon to induce cell growth directionality. An acute angle exists between the members of the arrow-like pairs of minor bases, while an obtuse angle exists between contiguous major and minor bases.
申请公布号 US2004077076(A1) 申请公布日期 2004.04.22
申请号 US20030338076 申请日期 2003.01.07
申请人 RICCI JOHN L.;ALEXANDER HAROLD;GREW JOHN 发明人 RICCI JOHN L.;ALEXANDER HAROLD;GREW JOHN
分类号 B01L3/00;B81B1/00;C12M1/20;(IPC1-7):C12M3/00 主分类号 B01L3/00
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