发明名称 |
Use of matrix metalloprotease inhibitors for the treatment of cancer |
摘要 |
The invention relates to the use of an active agent, particularly an inhibitor, in treating cancer by influencing, preferably inhibiting the expression of matrix-metalloproteases. The targets for this active agent can especially related to downstream regulators of the matrix-metalloprotease 9 (MMP-9) signal transduction pathway. According to the invention, especially inhibitors of p38beta and p38gamma as also of mitogen-activated kinase kinase 6 (MKK6) and mitogen-activated kinase kinase 3 (MKK3) can be applied.
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申请公布号 |
US2004067883(A1) |
申请公布日期 |
2004.04.08 |
申请号 |
US20030332903 |
申请日期 |
2003.08.29 |
申请人 |
SIMON CHRISTIAN;ZENNER HANS-PETER |
发明人 |
SIMON CHRISTIAN;ZENNER HANS-PETER |
分类号 |
A61K45/00;A61K31/00;A61K31/4439;A61K38/00;A61K48/00;A61P35/00;A61P43/00;(IPC1-7):A61K38/17 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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