发明名称 |
Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
摘要 |
Immunologically active polypeptides with no or reduced toxicity useful for the preparation of an antipertussis vaccine. Method for the preparation of said polypeptides which comprises, cultivating, a microorganism transformed with a hybrid plasmid including the gene/s which codes for at least one of said polypeptides in a suitable medium and recovering the desired polypeptide from the cells or from the culture medium.
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申请公布号 |
US6713072(B1) |
申请公布日期 |
2004.03.30 |
申请号 |
US19940261668 |
申请日期 |
1994.06.17 |
申请人 |
CHIRON S.R.L. |
发明人 |
PIZZA MARIAGRAZIA;BARTOLONI ANTONELLA;RAPPUOLI RINO |
分类号 |
A61K39/00;C07K14/235;C12N15/31;(IPC1-7):A61K39/10 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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