发明名称 APPARATUS FOR SKIN ABSORPTION ENHANCEMENT AND TRANSDERMAL DRUG DELIVERY
摘要 <p>Application of electrical pulses is made in a controlled manner, in order to increase the absorption of substances applied previously on the skin. Optionally, mechanical vibrations may also be provided to the skin to increase the absorption effect. The electrical pulses are provided to the skin by way of an array of electrodes disposed on a vibrating head plate, and the mechanical vibrations are provided to the skin by way of the vibrating head plate being made to vibrate (if that option is utilized). Preferably, the electrical and mechanical vibrations are at the same frequency and phase with respect to each other, in order to increase the absorption effect. Also, at the same time the electrical pulses are provided to the skin, a syringe containing a skin enhancement substance or a drug is actuated so as to move a particular amount of the substance from the skin, whereby the substance is passed through a tube and then into a groove surrounding a central electrode of the array of electrodes disposed on the plate. The substance is absorbed within the skin as a result.</p>
申请公布号 WO2004009177(A1) 申请公布日期 2004.01.29
申请号 WO2003IB02694 申请日期 2003.07.08
申请人 MATTIOLI ENGINEERING LTD.;BERNABEI, GIAN, FRANCO 发明人 BERNABEI, GIAN, FRANCO
分类号 A61H9/00;A61H23/02;A61H39/00;A61M37/00;A61N1/32;A61N7/00;(IPC1-7):A61N1/32 主分类号 A61H9/00
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