Inhalation powder containing the CGRP antagonist BIBN4096 and process for the preparation thereof

摘要

The invention relates to an inhalation powder for treating migraine, containing the CGRP antagonist 1-[N<2>-[3,5-dibromo-N-[[4-(3,4-dihydro-2(1H)-oxoquinazolin-3-yl)-1-piperidinyl]carbonyl]-D-tyrosyl]-L-lysyl]-4-(4-pyridinyl)-piperazine [BIBN4096] of formula I as the active substance base in the form of spherically nanostructured microparticles, and a process for the manufacture thereof.