Replication and differentiation of cells in vitro, useful e.g. for wound healing and tissue reconstruction, uses specific growth factors to initiate, end and structurally control growth

摘要

Replicating and differentiating cells in vitro in which the growth process is initiated or terminated and structurally controlled by use of the growth factors (GF) thrombopoietin (TPO); erythropoietin (EPO); growth hormone (GH, preferably human); somatostatin; leukemia inhibitory factor (LIF) and/or ciliary neurotrophic factor (CNTF), is new. Independent claims are also included for the following: (1) biological matrix or carrier structure (A) containing at least one of the specified GF; (2) preparing (A) by coating an optionally activated matrix or carrier with GF; and (3) device for performing the new methods. ACTIVITY : Osteopathic; Cardiant; Dermatological; Hepatotropic; Uropathic; Vulnerary; Antiinflammatory; Antidiabetic; Antiulcer; Vasotropic; Opthalmological. No biological data given. MECHANISM OF ACTION : Tissue Replacement Therapy.