发明名称 2-Aminopyridine compounds and use thereof as drugs
摘要 The present invention provides 2-aminopyridine compound having an excellent adenosine receptor (A1, A2a, A2b receptors) antagonism, which is represented by the following formula: (wherein, R<1 >represents cyano group, carboxyl group or an optionally substituted carbamoyl group; R<2 >represents hydrogen atom, hydroxyl group, an optionally substituted C1-6 alkoxy group, an optionally substituted C6-14 aromatic hydrocarbon cyclic group or an optionally substituted 5- to 14-membered aromatic heterocyclic group; and R<3 >and R<4 >are the same as or different from each other and each represents a C6-14 aromatic hydrocarbon cyclic group, a 5- to 14-membered non-aromatic heterocyclic group or a 5- to 14-membered aromatic heterocyclic group which may be substituted, respectively) or a salt thereof.
申请公布号 US2004006082(A1) 申请公布日期 2004.01.08
申请号 US20030333689 申请日期 2003.01.23
申请人 HARADA HITOSHI;ASANO OSAMU;MIYAZAWA SHUHEI;UEDA MASATO;YASUDA MASAHIRO;YASUDA NOBUYUKI 发明人 HARADA HITOSHI;ASANO OSAMU;MIYAZAWA SHUHEI;UEDA MASATO;YASUDA MASAHIRO;YASUDA NOBUYUKI
分类号 A61K31/44;A61K31/4409;A61K31/443;A61K31/4436;A61K31/444;A61K31/445;A61K31/455;A61P1/00;A61P1/10;A61P3/06;A61P3/10;A61P7/10;A61P9/10;A61P11/06;A61P19/10;A61P25/16;A61P25/28;A61P27/02;A61P43/00;C07D213/80;C07D213/82;C07D213/85;C07D401/04;C07D405/04;C07D405/14;C07D409/04;C07D409/14;(IPC1-7):A61K31/502;C0743/02;C07D213/84 主分类号 A61K31/44
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