| 发明名称 |
P27 PREVENTS CELLULAR MIGRATION |
| 摘要 |
This invention provides methods of preventing cellular migration and of treating cardiovascular diseases and tumor metastasis by increasing the intracelllular concentration of cyclin-dependent kinase inhibitor p27 or C3 exoenzyme or decreasing the intracellular concentration of Rho-kinase, and methods of identifying chemical compounds for use in such treatments. |
| 申请公布号 |
WO03106970(A2) |
申请公布日期 |
2003.12.24 |
| 申请号 |
WO2003US18970 |
申请日期 |
2003.06.12 |
| 申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OFNEW YORK |
发明人 |
MARKS, ANDREW, R.;MARX, STEVEN, O. |
| 分类号 |
G01N33/50;A61K31/395;A61K38/43;A61K45/00;A61P9/00;A61P9/10;A61P35/04;A61P43/00;C07K14/47;C12N5/06;C12Q1/02;C12Q1/48;G01N33/15;G01N33/574;(IPC1-7):G01N/ |
主分类号 |
G01N33/50 |
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