摘要 |
The invention relates to the genome sequence and the nucleotide sequences coding for polypeptides of cyanophage S-2L. According to the invention, the polypeptides include, but are not limited to, polypeptides involved in the synthesis, transcription and replication of purine bases. In particular, determining the genome of cyanophage S-2L is useful for supplying genes which, expressed in recombinant bacteria, enable the synthesis of DNA monomers incorporating base D (2,6 diaminopurine) instead of base A (adenine), thereby producing chemically-remodelled nucleic acids in the bacteria. |
申请人 |
INSTITUT PASTEUR;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);GENOSCOPE -CENTRE NATIONAL DE SEQUENCAGE;MARLIERE, PHILIPPE;KAMINSKI, PIERRE-ALEXANDRE;GALISSON, FREDERIQUE;BOUZON, MADELEINE;POCHET, SYLVIE;WEISSENBACH, JEAN;SAURIN, WILLIAM;ROBERT, CATHERINE;VICO, VIRGINIE |
发明人 |
MARLIERE, PHILIPPE;KAMINSKI, PIERRE-ALEXANDRE;GALISSON, FREDERIQUE;BOUZON, MADELEINE;POCHET, SYLVIE;WEISSENBACH, JEAN;SAURIN, WILLIAM;ROBERT, CATHERINE;VICO, VIRGINIE |