| 发明名称 |
PSEUDOPOLYMORPHIC FORMS OF 2-[2-[4-[BIS (4-FLUOROPHENYL) METHYL]-1-PIPERAZINYL] ETHOXY]ACETIC ACID DIHYDROCHLORIDE |
| 摘要 |
The present invention relates to new pseudopolymorphic forms of 2-[2-[4-[bis (4- fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic acid dihydrochloride, namel y, anhydrous 2-[2-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]ethoxy]acetic ac id dihydrochloride and 2-[2-[4-[bis(4-fluorophenyl)methyl]-1- piperazinyl]ethoxy]acetic acid dihydrochloride monohydrate. It also relates to processes for the preparation of these pseudopolymorphic forms and to pharmaceutical compositions containing them.
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| 申请公布号 |
CA2310318(C) |
申请公布日期 |
2003.10.21 |
| 申请号 |
CA19982310318 |
申请日期 |
1998.11.26 |
| 申请人 |
UCB, S.A. |
发明人 |
TIMMERMANS, JACQUES;DOGIMONT, CHARLES;FANARA, DOMENICO;BODSON, GUY;DELEERS, MICHEL;BERWAER, MONIQUE |
| 分类号 |
C07D295/08;A61K31/495;A61P11/08;A61P17/00;A61P25/08;A61P37/08;A61P43/00;C07D295/084;C07D295/088;(IPC1-7):C07D295/08 |
主分类号 |
C07D295/08 |
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