PREVENTION AND TREATMENT OF OXIDATIVE STRESS DISORDERS BY GLUTATHIONE AND PHASE II DETOXIFICATION ENZYMES
摘要
The present invention generally relates to the field of treating oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracellular levels of at least one Phase II detoxification enzyme in animal tissue. The present invention also relates to the field of protecting a subject from oxidative stress disorders by administering a pharmaceutically effective amount of a compound that elevates the intracellular levels of glutathone or intracellular levels of at least one Phase II detoxification enzyme in the subject. The present invention also relates to a pharmaceutical composition useful for the treatment of oxidative stress disorders.
申请公布号
WO03051313(A3)
申请公布日期
2003.10.16
申请号
WO2002US40457
申请日期
2002.12.18
申请人
JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE;GAO, XIANGQUN;DINKOVA-KOSTOVA, ALBENA, T.;TALALAY, PAUL
发明人
GAO, XIANGQUN;DINKOVA-KOSTOVA, ALBENA, T.;TALALAY, PAUL