| 摘要 |
A covalent conjugate of a 4'-hydroxyazobenzene-2-carboxylic acid derivative (HABA) and an avidin-type molecule, of the formula:wherein A is (CH<HIL><PDAT>2</SB><PDAT>)<HIL><PDAT>n </SB><PDAT>or -CH=CH-, wherein n is an integer from 0-10; B is (CH<HIL><PDAT>2</SB><PDAT>)<HIL><PDAT>n </SB><PDAT>wherein n is an integer from 2 to 10; m is zero or 1; and Av is the residue of an avidin-type molecule selected from the group comprising native egg-white avidin, recombinant avidin, deglycosylated avidins, bacterial streptavidin, recombinant streptavidin, truncated streptavidin and other derivatives of said avidin-type molecules. These HABAylated avidins are red colored in the quinone configuration and can be used in many applications in the avidin-biotin technology.</PTEXT>
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