发明名称 |
Method of enhancing the efficiency of a pharmaceutical business |
摘要 |
A method of doing business is disclosed whereby the process for selecting drug candidates is improved. The method involves the application of a technology which makes it possible to determine metabolic processes involved in the formation of any glucose-based metabolite. A precursor molecule is labeled with a stable carbon (<13>C) isotope at specific positions. The label is allowed to distribute and rearrange in the system. Metabolites are recovered and analyzed against a control system or known biochemical reactions and/or cycles to determine information such as metabolic pathway substrate flux caused by a compound acting on the system.
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申请公布号 |
US2003180710(A1) |
申请公布日期 |
2003.09.25 |
申请号 |
US20020192743 |
申请日期 |
2002.07.09 |
申请人 |
LEE WAI-NANG PAUL;BOROS LASZLO G. |
发明人 |
LEE WAI-NANG PAUL;BOROS LASZLO G. |
分类号 |
A61K51/04;G06F19/00;(IPC1-7):G06F17/60;C12Q1/00;G01N33/48;G01N33/50 |
主分类号 |
A61K51/04 |
代理机构 |
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主权项 |
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地址 |
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