METHOD OF SYNTHESIS FOR CYCLIC PEPTIDE UTILIZING HIGH- TEMPERATURE AND HIGH-PRESSURE WATER

摘要

PROBLEM TO BE SOLVED: To rapidly synthesis a cyclic peptide which is a functional material by using water as an environmental-friendly and inexpensive reaction solvent. SOLUTION: The cyclic peptide having an arbitrary amino acid sequence is synthesized by carrying out a dehydration/cyclization reaction of a linear peptide comprising various amino acids by using high-temperature and high- pressure water. COPYRIGHT: (C)2003,JPO