发明名称 |
PROMISCUOUS G-PROTEIN COMPOSITIONS AND THEIR USE |
摘要 |
Disclosed are compositions and methods for their use, such as in identifying G-protein coupled receptors and ligands and compounds that modulate signal transduction. The compositions and methods employ promicuous G-proteins. Activation of the promiscous G-protein can be detected in a variety of assays, including assays in which activation is indicated by a change in fluorescence emission of a sample that contains the composition. |
申请公布号 |
EP1012324(A4) |
申请公布日期 |
2003.08.13 |
申请号 |
EP19970932210 |
申请日期 |
1997.06.20 |
申请人 |
PANVERA LLC |
发明人 |
NEGULESCU, PAUL, A.;OFFERMANNS, STEFAN;SIMON, MELVIN;ZUKER, CHARLES |
分类号 |
C07K14/705;C12N15/85;G01N33/50 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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