发明名称 |
Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs |
摘要 |
The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, nitrogen-substituted thalidomide analogs and di-substituted thalidomide analogs have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
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申请公布号 |
US2003139451(A1) |
申请公布日期 |
2003.07.24 |
申请号 |
US20020213294 |
申请日期 |
2002.08.06 |
申请人 |
SHAH JAMSHED H.;CONNER BARRY P.;SWARTZ GLENN M.;HUNSUCKER KIMBERLY A.;ROUGAS JOHN;D'AMATO ROBERT J.;PRIBLUDA VICTOR;TRESTON ANTHONY |
发明人 |
SHAH JAMSHED H.;CONNER BARRY P.;SWARTZ GLENN M.;HUNSUCKER KIMBERLY A.;ROUGAS JOHN;D'AMATO ROBERT J.;PRIBLUDA VICTOR;TRESTON ANTHONY |
分类号 |
A61K31/4523;A61K31/454;A61P9/00;A61P27/02;C07D401/04;(IPC1-7):A61K31/454 |
主分类号 |
A61K31/4523 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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