发明名称 |
Oral administration of 6-hydroxy-oxymorphone for use as an analgesic |
摘要 |
In a method of treating pain, a patient is administered a pharmaceutical composition of 6-hydroxy oxymorphone in amount sufficient to induce analgesia. In one embodiment, the pharmaceutical composition is administered orally. Any known or later developed method of oral delivery may be used. To achieve the desired analgesic effect, blood plasma levels of 6-hydroxy oxymorphone are raised to at least approximately 0.2 ng/mL. Most preferably blood plasma levels of 6-hydroxy oxymorphone range at least 0.3 ng/mL during treatment. Administration of compositions containing 6-hydroxy oxymorphone, and one or more carriers, diluents, and excipients in an amount sufficient to induce analgesia is also contemplated.
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申请公布号 |
US2003130297(A1) |
申请公布日期 |
2003.07.10 |
申请号 |
US20020189897 |
申请日期 |
2002.07.03 |
申请人 |
ENDO PHARMACEUTICALS, INC. |
发明人 |
KAO HUAI-HUNG;SMITH-CARLISS RICHARD;MCCALL TROY;LEE DAVID |
分类号 |
A61K38/22;A61K9/20;A61K9/22;A61K31/485;A61P25/04;A61P29/00;C07D491/08;C07D491/107;(IPC1-7):A61K31/485 |
主分类号 |
A61K38/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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