Compounds, compositions and methods for modulating beta-amyloid production

摘要

Methods and compositions useful in the treatment of amyloidosis and conditions and diseases associated therewith, such as Alzheimer's disease, are provided. The methods involve administering to a subject in need thereof a pharmaceutical composition including one or more agents that modulate PPARalpha and/or PPARdelta activity, resulting in an inhibition of beta-amyloid production and/or release from cells of the subject, particularly brain cells.