发明名称 |
BONE DYSBOLISM DISEASE MARKER AND ITS UTILIZATION |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a disease marker reflecting a bone dysbolism disease associated with the enhancement of the differentiation and activation of osteoclasts, a method for detecting the bone dysbolism disease by utilizing the disease marker and a method for screening a medicine useful for the improvement of the disease. <P>SOLUTION: This polynucleotide having at least continued 15 bases and/or a polynucleotide complementary to it in a base sequence of a NF-ATc isoform a gene or Chloride intracellular channel 14 gene is utilized as the disease marker of the bone dysbolism disease associated with the enhancement of the differentiation and activation of the osteoclasts. <P>COPYRIGHT: (C)2003,JPO |
申请公布号 |
JP2003169687(A) |
申请公布日期 |
2003.06.17 |
申请号 |
JP20020136030 |
申请日期 |
2002.05.10 |
申请人 |
TAKEYA TATSUO;SUMITOMO PHARMACEUT CO LTD |
发明人 |
TAKEYA TATSUO;HAYASHI KOJI |
分类号 |
G01N33/50;A61K45/00;A61P19/00;A61P19/08;C07K16/18;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/68 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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