发明名称 |
GLYCERYLALDEHYDE-3-PHOSPHATE DEHYDROGENASE PROMOTER INDUCING CELL DEATH |
摘要 |
<p>Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) promoter DNA which induces cell death, and a screening method for an apoptosis-suppressing agent using it. According to this invention, an apoptosis-suppressing agent can be screened by measuring the promoter activity of the GAPDH gene which discovers specifically the GAPDH protein which guides cell death in cell death process using the host cell in which the transformation was carried out by the vector incorporating the GAPDH promoter DNA.</p> |
申请公布号 |
EP1308510(A1) |
申请公布日期 |
2003.05.07 |
申请号 |
EP20010955624 |
申请日期 |
2001.08.09 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
ISHITANI, RYOICHI |
分类号 |
C12N15/11;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N9/02;C12N15/85;C12Q1/02;C12Q1/68;(IPC1-7):C12N15/11 |
主分类号 |
C12N15/11 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|