| 发明名称 |
PHARMACEUTICAL DOSAGE FORM OF AMORPHOUS NELFINAVIR MESYLATE |
| 摘要 |
A solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate is provided comprising amorphous nelfinavir mesylate, and a pharmaceutically acceptable, water soluble, non-ionic synthetic block copolymer of ethylene oxide and propylene oxide, said copolymer having a melting point of at least 40 DEG C. A hot melt granulation process for making the dosage form is provided. |
| 申请公布号 |
WO02089835(A3) |
申请公布日期 |
2003.05.01 |
| 申请号 |
WO2002EP04711 |
申请日期 |
2002.04.29 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
INFELD, MARTIN, HOWARD;PHUAPRADIT, WANTANEE;SHAH, NAVNIT, HARGOVINDAS;ZHANG, LIN |
| 分类号 |
A61K9/16;A61K9/14;A61K9/20;A61K9/48;A61K31/472;A61K38/55;A61K47/34;A61P31/12;A61P31/18;A61P43/00 |
主分类号 |
A61K9/16 |
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