| 摘要 |
PURPOSE: A composition of a radiation sensitizing agent which contains an extract of Fomitella fraxinea(Bull.: Fr.) Ryv. as an active ingredient is provided to minimize adverse effect of radiation and to allow the composition to exhibit excellent sensitizing effect on radiation. CONSTITUTION: The composition of a radiation sensitizing agent contains 0.01 to 50% by weight of an extract of Fomitella fraxinea obtained by extraction with a solvent selected from ethanol, methanol, butanol and propanol. For an example, Fomitella fraxinea is dried and ground. 50g of Fomitella fraxinea powder is extracted in 10L aqueous methanol solution, followed by reaction at 40deg.C for 3 days, filtration and freeze- drying to produce 150g of Fomitella fraxinea extract. The composition has an LD50 value of 400mg/1kg(body weight).
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