发明名称 |
METHODS OF USING 18903 TO TREAT PAIN AND PAIN-RELATED DISORDERS |
摘要 |
The invention provides isolated nucleic acid molecules, designated COE-2 nucleic acid molecules, which encode novel carboxyl lesterase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing COE-2 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a COE-2 gene has been introduced or disrupted. The invention still further provides isolated COE-2 proteins, fusion proteins, antigenic peptides and anti-COE-2 antibodies. Diagnostic and therapeutic methods utilizing compositions of the invention are also provided. |
申请公布号 |
WO0244357(A3) |
申请公布日期 |
2003.02.13 |
申请号 |
WO2001US45356 |
申请日期 |
2001.11.30 |
申请人 |
MILLENNIUM PHARMACEUTICALS, INC.;KAPELLER-LIBERMANN, ROSANA;SILOS-SANTIAGO, INMACULADA |
发明人 |
KAPELLER-LIBERMANN, ROSANA;SILOS-SANTIAGO, INMACULADA |
分类号 |
A61K38/00;C12N9/18 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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