发明名称 Recombinant vaccine against dengue virus
摘要 A recombinant protein encompassing the complete envelope glycoprotein and a portion of the carboxy-terminus of the membrane/premembrane protein of dengue 2 virus was expressed in baculovirus as a protein particle. The recombinant protein particle was purified and found to provide protection against lethal challenge with dengue 2 virus in mice.
申请公布号 US6514501(B1) 申请公布日期 2003.02.04
申请号 US19990468517 申请日期 1999.12.21
申请人 THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 发明人 KELLY EILEEN P.;KING ALAN D.
分类号 A61K39/00;C07K14/18;(IPC1-7):A61K39/12 主分类号 A61K39/00
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