| 摘要 |
PyridoÄ3,2-eÜpyrazinone derivs. of formula (I) and their salts are new: A = CH2, NR<3> or O; X, Y, Z = N or CR<4>, provided that ≥ 1 of X, Y and Z is N; R<1> = H (but only if A = NR<3>); 1-10C alkyl, 1-10C alkenyl, 1-10C alkynyl, or 5-7C cycloalkyl (all opt. mono- or poly-substd. by OH, 1-6C alkoxy, 1-6C alkenyloxy or 1-6C alkynyloxy; aryl, aryloxy, heteroaryl or heteroaryloxy (all opt. substd.); opt. substd. amino, halo, NO2, CN, C=OR<5> or S(O)nR<6>); n = 0-2; R<2> = H; 1-10C alkyl, 1-10C alkenyl, 1-10C alkynyl or 5-7C cycloalkyl (all opt. substd. as for R<1>); R<3> = H or 1-6C alkyl; R<4> = H, 1-6C alkyl (opt. substd.) or halo; R<5> = H, 1-6C alkyl (opt. substd.), Ph, OH or 1-6C alkoxy; aryloxy or amino (both opt. substd.); R<6> = H, 1-6C alkyl, aryl (opt. substd.), OH or 1-6C alkoxy; aryloxy or amino (both opt. substd.). |
