发明名称 |
Pharmaceutical compositions comprising recombinant human acid alpha-glucosidase containing mannose 6-phosphate |
摘要 |
<p>The present invention relates to pharmaceutical composition comprising a lysosomal protein, in particular recombinant human acid alpha -glucosidase containing mannose 6-phosphate, optionally phosphorylated at the 6' position of its mannose group, and a pharmaceutically acceptable carrier; the use of such proteins for the preparation of pharmaceuticals, in particular for the treatment of Pompe's disorder and methods for the production of the same.</p> |
申请公布号 |
EP1262191(A1) |
申请公布日期 |
2002.12.04 |
申请号 |
EP20020018187 |
申请日期 |
1996.07.31 |
申请人 |
PHARMING INTELLECTUAL PROPERTY BV;ERASMUS UNIVERSITEIT ROTTERDAM;ACADEMIC HOSPITAL ROTTERDAM |
发明人 |
REUSER, ARNOLD, J.J.;VAN DER PLOEG, ANS, T.;PIEPER, FRANK, R.;VERBEET, MARTIN, PH. |
分类号 |
A61P21/00;C12N9/26;C12N15/56;(IPC1-7):A61K38/47 |
主分类号 |
A61P21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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