| 摘要 |
<p>A method for reducing copper levels in a patient and for treatin copper toxicosis and Wilson's Disease is disclosed that includes administering to the patient a therapeutically effective amount of an amine polymer, wherein the amine polymer is substantially water-insoluble or non-aborbent in the gastrointestinal tract. In one embodiment, the amine polymer is aliphatic. Examples of polmers that are useful in an embodiment of the invention includes sevelamer hydrogen chloride and colesevelam. The invention includes the use of amine polymers such as a cross-linked polymer characterized by a repeat unit having the formula (1) and salts and copolmers thereof, where n is a positive and x is zero or an integer between 1 and about 4. Also described is a use, for the manufacture of a medicament, of a polymer that reduces copper levels in a patient.</p> |
