PROCESS FOR PREPARING O-ACETYL-L SERINE BY FERMENTATION

摘要

PURPOSE: Provided is a fermentative process which provides high yields of O-acetyl-L-serine despite the instability of O-acetyl-L-serine and the negative physiological consequences of efficiently exporting O-acetyl-L-serine from the cell. CONSTITUTION: The process for a fermentative preparation of O-acetyl-L-serine, comprises the steps of: culturing a microorganism strain, which is derived from a wild type and which exhibits an increased endogenous formation of O-acetyl-L-serine and an increased efflux of O-acetyl-L-serine as compared with the wild type, in a fermentation medium; and setting a pH in the range from 5.1 to 6.5 in the fermentation medium.