发明名称 |
Inhibitors of farnesyl-protein transferase |
摘要 |
Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.
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申请公布号 |
US6432959(B1) |
申请公布日期 |
2002.08.13 |
申请号 |
US19990469465 |
申请日期 |
1999.12.22 |
申请人 |
SCHERING CORPORATION |
发明人 |
COOPER ALAN B.;DOLL RONALD J.;FERREIRA JOHAN A.;GANGULY ASHIT;GIRIJAVALLABHAN VIYYOOR M.;TAVERAS ARTHUR G.;CHAO JIANPING;BALDWIN JOHN J.;HUANG CHIA-YU;LI GE |
分类号 |
A61P35/00;C07D401/14;C07D403/12;C07D417/14;(IPC1-7):A61K31/496;C07D411/14 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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