发明名称 |
Active immunization using a siderophore receptor protein |
摘要 |
The invention provides a vaccine for immunizing poultry and other animals against infection by a gram-negative bacteria, and a method of immunizing an animal using the vaccine. The vaccine may contain purified siderophore receptor proteins derived from a single strain or species of gram-negative bacteria or other organism, which are cross-reactive with siderophores produced by two or more strains, species or genera of gram-negative bacteria. The invention further provides a process for isolating and purifying the siderophore receptor proteins, and for preparing a vaccine containing the proteins. Also provided is a method for diagnosing gram-negative sepsis.
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申请公布号 |
US6432412(B1) |
申请公布日期 |
2002.08.13 |
申请号 |
US19990361081 |
申请日期 |
1999.07.26 |
申请人 |
WILLMAR POULTRY COMPANY, INC. |
发明人 |
EMERY DARYLL A.;STRAUB DARREN E.;HUISINGA RICHARD;CARLSON BETH A. |
分类号 |
A61K39/102;A61P31/04;G01N33/569;(IPC1-7):A61K39/02;A61K39/38;A61K39/116;A61K45/00;A61K39/108 |
主分类号 |
A61K39/102 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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