发明名称 |
Bovine tumor necrosis factor receptor-1 and methods of use |
摘要 |
The invention relates to nucleic acid sequences encoding a bovine tumor necrosis factor receptor-I (TNF-RI). Also within the invention is a soluble bovine TNF-RI, which is a potent inhibitor of bovine tumor necrosis factor-alpha (TNF-alpha). The invention demonstrates that soluble bovine TNF-RI has therapeutic value as an inhibitor of TNF in cattle suffering from coliform mastitis or other inflammatory disease.
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申请公布号 |
US2002076765(A1) |
申请公布日期 |
2002.06.20 |
申请号 |
US20010970532 |
申请日期 |
2001.10.03 |
申请人 |
IOWA STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
TAYLOR MICHAEL J.;KEHRLI MARCUS E.;LEE EUN-KYUNG;MWANGI SIMON |
分类号 |
C07K14/705;(IPC1-7):C07K14/715;C07H21/04;C12P21/02;C12N5/06 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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