发明名称 |
Papillomavirus: biosynthetic process and assays |
摘要 |
The present invention provides a process of biosynthesizing papillomavirus by inducing complete differentiation of an epithelial cell that contains papillomavirus DNA. Complete differentiation is induced by exposing epithelial cells to a protein kinase C inducer. Assays for screening agents that modify papillomavirus biosynthesis, determining the papillomavirus infectivity of epithelial cells, detecting the presence of anti-papillomavirus antibodies and vaccinating against papillomavirus infection are also provided.
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申请公布号 |
US6399353(B1) |
申请公布日期 |
2002.06.04 |
申请号 |
US19940208807 |
申请日期 |
1994.03.10 |
申请人 |
MEYERS CRAIG M.;LAIMINS LAIMONIS A. |
发明人 |
MEYERS CRAIG M.;LAIMINS LAIMONIS A. |
分类号 |
A61K39/12;C12N5/071;C12N7/02;G01N33/50;G01N33/569;(IPC1-7):C12N7/00;C12N5/08;C12N5/10 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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