发明名称 |
Inhibition of transglutaminase-mediated microbial interaction with a mammalian host |
摘要 |
The infection of a mammalian host by a microorganism can be prevented or treated through the administration of substrates for transglutaminases or antibodies against such substrates that inhibit the transglutaminase-mediated interaction of the microorganism with the mammalian host. These compounds may be used in the identification, prevention or treatment of microbial infection of mammalian hosts such as immunocompromised or immunosuppressed humans, for example, those having AIDS or undergoing transplantation or anti-cancer therapy.
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申请公布号 |
US6388056(B1) |
申请公布日期 |
2002.05.14 |
申请号 |
US19980178509 |
申请日期 |
1998.10.26 |
申请人 |
SUNDSTROM PAULA |
发明人 |
SUNDSTROM PAULA;BRADWAY STEVEN D. |
分类号 |
G01N33/569;A61K38/00;A61K39/00;A61K39/02;A61K39/12;A61K39/395;A61P31/00;A61P31/04;A61P31/10;A61P31/18;A61P43/00;C07K14/00;C07K14/40;C07K16/00;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;G01N33/577;(IPC1-7):C07K14/40 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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