| 发明名称 |
NOVEL POLYMORPHIC FORMS OF 5-[4-[2-[N-METHYL-N-(2-PYRIDYL)AMINO]ETHOXY]BENZYL] THIAZOLIDINE-2,4-DIONE MALEATE AND PROCESS FOR THEIR PREPARATION |
| 摘要 |
<p>This invention relates to novel polymorphic/pseudopolymorphic forms of 5-[4- [2[N-methyl-N-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate having formula (I). The invention also relates to a pharmaceutical compositi on comprising the novel polymorphic form or their mixture and a pharmaceuticall y acceptable carrier. The polymorphic forms of the present invention are more active, as antidiabetic agent, than the hitherto known 5-[4-[2-[N-(2-methyl- N- (2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate.</p> |
| 申请公布号 |
CA2426117(A1) |
申请公布日期 |
2002.04.04 |
| 申请号 |
CA20012426117 |
申请日期 |
2001.09.25 |
| 申请人 |
DR. REDDY'S RESEARCH FOUNDATION |
发明人 |
GADDAM, OM REDDY;SEELLA, VISHNUVARDHAN REDDY;KRISHNAMURTHI, VYAS;MAMILLAPALLI, RAMABHADRA SARMA;CHEBIYYAM, PRABHAKAR |
| 分类号 |
A61K31/4439;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P19/10;C07D277/34;C07D417/12;(IPC1-7):C07D417/12;A61K31/425 |
主分类号 |
A61K31/4439 |
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