摘要 |
<p>The invention discloses a new kind of polypeptide - HOMO DNA topoisomerase II-beta(TOP2B) 29.48 and polynucleotide encoding said polypeptide and a process for producing said polypeptide by DNA recombinant methods. It also discloses the method of applying the polypeptide for the treatment of various kinds of diseases, such as chromosome disease, geneogenous deformity and dysgenopathy. Antagonist and the therapeutic use of the polypeptide is also disclosed. In addition, it refers to the use of polynucleotide encoding said HOMO DNA topoisomerase II-beta(TOP2B)29.48.</p> |