| 发明名称 |
Recombinant IL-18 antagonists intended for treating diseases mediated by IL-18 |
| 摘要 |
<p>Chimeric, humanized and other IL-18 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.</p> |
| 申请公布号 |
CZ20013362(A3) |
申请公布日期 |
2002.03.13 |
| 申请号 |
CZ20010003362 |
申请日期 |
2000.03.17 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION;SMITHKLINE BEECHAM PLC |
发明人 |
HOLMES STEPHEN D.;HO YEN SEN;TAYLOR ALEXANDER HARRISON;ABDEL-MEGUID SHERIN S. |
| 分类号 |
G01N33/53;A61K39/395;A61P1/04;A61P3/10;A61P17/06;A61P19/02;A61P25/00;A61P37/00;C07K16/24;C12N5/10;C12N15/02;C12N15/12;C12P21/08;C12R1/91;G01N33/577;(IPC1-7):C07K16/18;C12N5/12 |
主分类号 |
G01N33/53 |
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