发明名称 |
Specific immune system modulation |
摘要 |
Methods and pharmaceutical compositions for modifying the immune response of a mammal to a specific antigen are provided. The methods include treating an antigen presenting cell to enhance expression of a major histocompatibility complex molecule and reacting the treated antigen presenting cell with the antigen extracorporeally to form an antigen-associated antigen presenting cell.
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申请公布号 |
US6355238(B1) |
申请公布日期 |
2002.03.12 |
申请号 |
US19970822940 |
申请日期 |
1997.03.21 |
申请人 |
YALE UNIVERSITY |
发明人 |
EDELSON RICHARD L.;GASPARRO FRANCIS P.;TIGELAAR ROBERT E. |
分类号 |
A61K38/00;A61K35/14;A61K39/00;A61K39/35;A61K39/39;A61K41/00;A61P17/00;A61P37/00;C07K14/475;C12N13/00;(IPC1-7):A01N63/00;A01N65/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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