发明名称 3-(PYRROL-2-YLMETHYLIDENE)-2-INDOLINONE DERIVATIVES AND THEIR USE AS PROTEIN KINASE MODULATORS
摘要 The present invention is directed to prodrugs of certain 3-(pyrrol-2-yl-methylidene)-2-indolinone derivatives that modulate the activity of protein kinases ("PKs"). Pharmaceutical compositions comprising these compounds, methods of treating diseases related to abnormal PK activity utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
申请公布号 WO0190103(A9) 申请公布日期 2002.03.07
申请号 WO2001US16741 申请日期 2001.05.24
申请人 SUGEN, INC.;PHARMACIA & UPJOHN COMPANY;MOON, MALCOLM, WILSON;MOROZOWICH, WALTER;GAO, PING;KOENIG, MARCEL 发明人 MOON, MALCOLM, WILSON;MOROZOWICH, WALTER;GAO, PING;KOENIG, MARCEL
分类号 C07D401/06;A61K31/404;A61K31/4045;A61K31/4439;A61K31/496;A61K31/661;A61P1/00;A61P1/16;A61P3/00;A61P3/10;A61P7/02;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P13/12;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P19/04;A61P25/00;A61P25/28;A61P29/00;A61P31/00;A61P31/04;A61P35/00;A61P37/00;A61P37/06;A61P43/00;C07D401/14;C07D403/06;C07D403/14;C07F9/572;C07F9/6558;(IPC1-7):C07D403/06;C07F9/09 主分类号 C07D401/06
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