| 摘要 |
PROBLEM TO BE SOLVED: To provide a safe method for producing 2'-O-alkylguanosine from 2,6-diaminopurine riboside, excellent in operability and practicality. SOLUTION: This method for producing the 2'-O-alkylguanosine from the 2,6-diaminopurine riboside is characterized in that the 2,6-diaminopurine riboside is treated with an alkylated phosphoric acid or an alkylated sulfuric acid by using a water-based solvent as a solvent under a basic condition to provide 2'-O-alkyl-2,6-diaminopurine riboside, and the 2'-O-alkyl-2,6-diaminopurine riboside is deaminated to provide the objective 2'-O-aminoguanosine.
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