| 摘要 |
The present invention provides a physiologically active peptide, a DNA encoding the peptide, an antibody which recognizes the peptide, and application methods thereof useful in screening and developing a therapeutic agent for diseases which accompany infection and inflammation, diseases which accompany abnormal differentiation and proliferation of smooth muscle cells, diseases which accompany abnormal activation of fibroblasts, diseases which accompany abnormal activation of a synovial tissue, diseases which accompany disorder of pancreatic beta cells, diseases which accompany abnormality of osteoblasts or osteoclasts, diseases which accompany abnormal activation of immunocytes, diseases which accompany disorder of a blood vessel, diseases of an eye based on angiogenesis, diseases which accompany neopla, diseases in which linkage to gene regions of a major histocompatibility antigen is confirmed, and the like. |
