摘要 |
Compounds of the general formula (¦), which exhibit selective muscarinic M3 receptor antagonism, little have side effects, and are suitable for administration by inhalation and useful as therapeutic agents for respiratory system diseases or the like: (¦) wherein A is a group of the general formula (a0) or (b0): (a0) (b0) Ar is aryl or heteroaryl, any of which may be substituted; B<1> and B<2> are each an aliphatic hydrocarbon group; R<1> is fluorinated cycloalkyl; R<2>, R<3> and R<4> are each lower alkyl, or a single bond or alkylene, any of which is bonded to B<1>, or alternatively R<2> and R<3> may be united to form alkylene; R<5> and R<7> are each hydrogen, lower alkyl, or a single bond or alkylene, any of which is bonded to B<2>; R<6> is hydrogen, lower alkyl, or N(R<8>)R<9>; and X<-> is an anion.
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