Antitumor-forbindelser, farmasöytisk blanding og fremgangsmåter for fremstilling derav

摘要

The present invention is directed to novel taxanes useful as chemotherapeutic agents or their precursors. Processes for preparing the novel taxanes include coupling reactions, in the presence of a base, of baccatin of formula (III) or (IV) rmula (V). (V) The invention also provides pharmaceutical compositions including the novel taxanes and method for treatment of certain cancers with these new compounds.