TRANSFECTION OF LUNG VIA AEROSOLIZED TRANSGENE DELIVERY

摘要

PROBLEM TO BE SOLVED: To provide a method and a composition capable of expressing a foreign gene in an airway cell of a mammal. SOLUTION: Lipid carrier-nucleic acid complexes are prepared, then delivered via aerosol to the lung airway. This invention provides a direct method for transforming pulmonary cells as a means for treating disorders of the lung as for providing a means for delivering substances systematically in the following expression in the lung.