Automated testing of activity of cell-modifying agents useful for selecting cytostatic agents for particular treatments

摘要

Automated detection of an activity of a cell-modifying agent (A) on living cells. The process comprises: (a) measuring data (MD) that represents cellular activity of live cells contacted with (A); (b) normalizing with similar data (MD') derived from cells not treated with (A) and/or treated only with the solvent used to apply (A); (c) comparing normalized data with reference values (corresponding to untreated and/or solvent-treated cells); and (d) data that represent the effect the effect of (A) on the cells are output. Independent claims are also included for the following: (1) an apparatus for the new method; and (2) a computer program package for implementing the method.