发明名称 |
Methods for enhancing oral tolerance and treating autoimmune disease using inhibitors of interleukin-12 |
摘要 |
The present invention provides a method for enhancing oral tolerance to an antigen associated with an autoimmune disease in a subject having the autoimmune disease comprising orally administering to the subject an antigen associated with the autoimmune disease and administering an inhibitor of interleukin-12 in amounts sufficient to enhance oral tolerance. Also provided in the present invention is a method for treating or preventing an autoimmune disease in a subject comprising orally administering to the subject an antigen associated with the autoimmune disease and administering an inhibitor of interleukin-12 in amounts sufficient to treat or prevent the autoimmune disease, thereby treating or preventing the autoimmune disease.
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申请公布号 |
US2001051159(A1) |
申请公布日期 |
2001.12.13 |
申请号 |
US20000732502 |
申请日期 |
2000.12.07 |
申请人 |
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发明人 |
STROBER WARREN;KELSALL BRIAN;MARTH THOMAS |
分类号 |
A61K39/395;C07K16/24;(IPC1-7):A61K39/395 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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