发明名称 |
SEQUENCE-SPECIFIC DNA RECOMBINATION IN EUKARYOTIC CELLS |
摘要 |
The invention relates to a method for carrying out the sequence-specific recombination of DNA in eukaryotic cells comprising the following steps: inserting a first DNA sequence into a cell; inserting a second DNA sequence into a cell, and; carrying out the sequence-specific recombination using the action of a bacteriophage lambda integrase Int. A preferred embodiment of the invention relates to a method that additionally comprises the step of carrying out a second sequence-specific recombination of DNA using the action of an Int and of an Xis factor. The invention also relates to vectors and to their use as medicaments. |
申请公布号 |
WO0116345(A3) |
申请公布日期 |
2001.12.06 |
申请号 |
WO2000DE02947 |
申请日期 |
2000.08.29 |
申请人 |
DROEGE, PETER;CHRIST, NICOLE;LORBACH, ELKE |
发明人 |
DROEGE, PETER;CHRIST, NICOLE;LORBACH, ELKE |
分类号 |
A01K67/027;A61K31/711;A61K35/76;A61K38/00;A61K48/00;A61P3/06;A61P7/00;A61P17/00;A61P21/04;A61P37/02;C12N5/10;C12N15/09;C12N15/90;C12R1/91 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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