| 摘要 |
The invention disclosed a new kind of human guanine nucleotide exchange factor 10 and the polynucleotide encoding said polypeptideand a process for producing the polypeptide by recombinant methods. It also disclosed the method of applying the polypeptide for the treatment of various kinds of diseases, such as cancer, hemopathy, HIV infection, immune diseases and inflammation. The antagonist of the polypeptide and therapeutic use of the same is also disclosed. In addition, it refers to the use of polynucleotide encoding said human guanine nucleotide exchange factor 10. |
